Effects of Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract on Postprandial Triglyceride Levels: A Double-blinded Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Postprandial triglyceride
研究概览
简要总结
The objectives of the study were to investigate effects of foods prepared in palm oil blended with canola oil containing surfactants and green tea extract on postprandial triglyceride levels in healthy volunteers. There were 22 subjects in the study. They were divided into 2 groups: 1.comsumed foods fried in palm oil blended with canola oil containing surfactants and green tea extract and 2.comsumed foods fried in palm oil. Postprandial triglyceride, lipid profiles, and liver and kidney functions were evaluated before and after taking 5 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female participants aged 18-60 years.
- •Participants with fasting triglyceride levels <150 mg/dL (after fasting for at least 8-12 hours before blood collection).
- •Participants without a history of cardiovascular disease, diabetes mellitus, thyroid disease, cancer, liver disease, or kidney disease.
- •Participants who are able to read and write.
- •Participants who voluntarily agree to participate after receiving information regarding the study objectives, procedures, potential risks, and expected benefits; are able to comply with the study protocol; and provide written informed consent.
排除标准
- •Participants with a history of allergy or adverse reactions, such as skin, respiratory, or gastrointestinal symptoms, after consuming foods containing canola oil, polyglycerol esters of fatty acids (PGEs), green tea extract, palm oil, or banana.
- •Participants who have consumed medications, dietary supplements, herbal products, or foods that may affect metabolism, such as weight-loss products or L-carnitine, within 2 weeks prior to enrollment.
- •Participants who regularly use medications that may affect lipid metabolism or blood lipid levels, such as corticosteroids or lipid-lowering agents.
- •Participants with serious underlying diseases or poorly controlled medical conditions, such as cancer, cardiovascular disease, or immunodeficiency disorders.
- •Participants with impaired liver or kidney function, defined as AST/ALT levels >3 times the upper limit of normal or kidney disease with an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m².
- •Female participants who are pregnant or breastfeeding.
- •Participants who regularly smoke.
- •Participants who regularly consume alcohol.
- •Participants who are currently participating in another research study.
研究组 & 干预措施
Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extrac
Take fried foods prepared in palm oil blended with canola oil containing surfactants and green tea extract 7 pieces.
干预措施: Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract (Other)
Control group
Take fried foods prepared in palm oil 7 pieces
干预措施: Fried Foods Prepared in Palm Oil (Other)
结局指标
主要结局
Postprandial triglyceride
时间窗: 5 hours
Postprandial triglyceride in blood
次要结局
- High Density Lipoprotein in blood(5 hours)
- Low Density Lipoprotein in blood(5 hours)
- Fasting blood glucose(5 hours)
- Creatinine in blood(5 hours)
- Blood Urea Nitrogen(5 hours)
- Aspartate Aminotransferase in blood(5 hours)
- Alanine Aminotransferase in blood(5 hours)
- Alkaline Phosphatase in blood(5 hours)
- Plasma antioxidant(5 hours)
- Total cholesterol in blood(5 hours)
研究者
Pornanong Aramwit, Pharm.D., Ph.D
Professor
Chulalongkorn University