NCT04290416Unknown不适用
Human Single Neuron Recordings in Epilepsy Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Single unit recordings
研究概览
简要总结
This study uses single neuron recordings in pre-surgical epilepsy patients to uncover the neural mechanisms underlying memory formation and retrieval. A secondary aim is to improve diagnostic tools to identify epileptogenic tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Interest in participation.
- •Temporal lobe epilepsy that is clinically being investigated with implantations of depth electrodes as part of the pre-surgical epilepsy monitoring.
- •Cognitive/language skills sufficient to follow experimental instruction and maintain focus on the experiment.
排除标准
- •Patient does not want to participate.
- •Extra-temporal epilepsy, or electrode implantation strategy that does not allow the use of micro-macrowire electrodes.
- •Cognitive/language skills insufficient to follow experimental instruction and maintain focus on the experiment.
结局指标
主要结局
Single unit recordings
时间窗: 14 days (patient in hospital for this length of time)
Activity of individual neurons will be recorded via micro wire electrodes
次要结局
- Intracranial electroencephalogram (iEEG)(14 days (patient in hospital for this length of time))
- Behavioural response data(14 days (patient in hospital for this length of time))
研究者
研究点 (2)
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