Combination gefitinib and methotrexate to treat ectopic pregnancies II - GEM for Ectopic Pregnancies II

Monash University0 个研究点目标入组 30 人开始时间: 2011年9月28日最近更新: 2019年6月30日

试验速览

暂无简介。

•1. Women aged between 18 and 45 inclusive
•2. Women with serum hCG greater than 5
•3. Women with either a mass which on ultrasound has the appearance of an ectopic pregnancy or a pregnancy of unknown location
•4. No clinical evidence of intra-uterine bleeding
•5. No pallor
•6. No guarding/rigidity on abdominal examination
•7. Stable blood pressure and heart rate
•8. Normal haemaglobin on full blood examination at day 1.
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 50
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range 0

•1. History of significant pulmonary disease (eg lung carcinoma including mesothelioma, chronic obstructive airways disease, emphysema, pneumonitis, silicosis, pulmonary fibrosis, severe/brittle asthma, ILD)
•2. Abnormal liver indices
•3. Abnormal renal indices
•4. Abnormal haematological indices
•5. Significant pre-existing dermatological condition (eg psoriasis, excema)
•5. Significant pre-existing gastrointestinal illness (eg inflammatory bowel disease, bowel carcinoma)
•6. Japanese ethnicity.

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