NCT01051947撤回不适用
Impact of Nebivolol on Central Aortic Pressure
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Stable blood pressure
研究概览
简要总结
A randomized, cross-over, single-blind study to compare the effects of nebivolol and metoprolol on central aortic pressure and peripheral brachial pressure in patients with stable cardiovascular disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with history of hypertension
- •Subjects who have received metoprolol for a minimum of 3 months
排除标准
- •Patients who have had an acute myocardial infarction, coronary revascularization or who have been hospitalized for heart failure or cardiac arrhythmia in the past 6 months
研究组 & 干预措施
Metoprolol
Experimental
Metoprolol therapy for 2-6 weeks depending on blood pressure readings
干预措施: Metoprolol (Drug)
Nebivolol
Experimental
Nebivolol therapy for 2-6 weeks depending on blood pressure readings
干预措施: Nebivolol (Drug)
结局指标
主要结局
Stable blood pressure
时间窗: 6 months
Subjects will be randomized to nebivolol or metoprolol. Their medication will be titrated so that their blood pressure is within 10% of their initial reading.
次要结局
未报告次要终点
研究者
研究点 (1)
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