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临床试验/NCT01110395
NCT01110395已完成不适用

31P Magnetic Resonance Spectroscopy of Heart

Washington University School of Medicine2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2009年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
2
主要终点
An MR Spectroscopy Showing Signal to Noise Ratio to Determine the Level of Heart Failure

研究概览

简要总结

Heart needs constant supply of energy to continue working. Phosphorus magnetic resonance spectroscopy allows us to measure energy produced in the heart. The purpose of this study is to determine if the energy production is reduced in failing heart.

详细描述

We will use non-invasive phosphorus magnetic resonance spectroscopy technique to measure creatine kinase (CK) flux in failing heart. The studies will be done on Siemens 3.0T human system. We will recruit subjects with LV dysfunction due to prior anterior wall myocardial infarction.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Individuals with left ventricular dysfunction

排除标准

  • Age < 18, pregnant, history of excessive alcohol use, or any condition (e.g. claustrophobia, a pacemaker) that would prevent him/her from completing the magnetic resonance spectroscopy study

结局指标

主要结局

An MR Spectroscopy Showing Signal to Noise Ratio to Determine the Level of Heart Failure

时间窗: 1-2 days

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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