Study on the correlation between the common TCM syndromes of gout and intestinal flora

Yunnan Hospital of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

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•Inclusion criteria of case group :(1) meet the diagnostic criteria of primary gout; (2) TCM syndrome differentiation belongs to damp-heat accumulation type or spleen deficiency dampness resistance type; (3) 18-70 years old; (4) Voluntarily participate in the study and sign the informed consent to enter the clinical study; (5) No gastrointestinal diseases, no antibiotics, gastrointestinal drugs or probiotics in the past 2 months;
•Control group inclusion criteria :(1) non-gout and hyperuricemia; (2) Exclude metabolic diseases, such as diabetes, obesity and hyperlipidemia; (3) No gastrointestinal diseases, no antibiotics, gastrointestinal motility drugs or probiotics in the past 2 months; (4) 18-70 years old; (5) As far as possible from the same region as the case group.

•(1) those who have taken antibiotics, probiotics and prebiotics within 2 weeks;(2) Secondary hyperuricemia and gout, such as congenital metabolic disease, myeloproliferative disease, advanced hypertension, diabetic ketoacidosis caused by hyperuricemia, renal failure, tumor chemotherapy and/or radiotherapy, etc.;(3) arthropathy caused by rheumatoid arthritis, suppurative arthritis, traumatic arthritis, psoriatic arthritis, pseudogout, lupus erythematosus and other diseases;(4) Blood creatinine = 133umol/ L;(5) patients with major organ failure or mental illness, tumor and other diseases;(6) Bmi = 50 or alcoholics;(7) pregnant and lactating women;(8) Exclude metabolic diseases, especially those affecting intestinal flora;(9) persons under the age of 18 or over 70;

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