Continuous Versus Interval Walking Training in Patients With Severe Chronic Obstructive Pulmonary Disease - a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- perceived exertion for dyspnea during walking training
研究概览
简要总结
This study will investigate the effects of interval walking training versus continuous walking training in patients with chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized to one of the two intervention groups. All walking training sessions will be performed on the same treadmill. Walking intensity in the continuous walking group will be 60 percent of the average speed of the 6-minute walking test. Patients in the interval training group will perform high intensity intervals at 120% of the 6-minute walking test speed for 60 seconds alternating with 60 seconds of rest. The total exercise duration will be progressively increased from 10 to 32 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COPD stage III or IV according to the Global Initiative for chronic obstructive lung disease [GOLD]
- •stationary patient in the Schön Klinik Berchtesgadener Land
排除标准
- •acute, severe exacerbation of COPD
- •failure to comply with study process
结局指标
主要结局
perceived exertion for dyspnea during walking training
时间窗: day 1 to 21
measured via modified Borg scale (0 to 10)
次要结局
- 6-minute walking test(day 1 to 21)
- heart rate during walking training(day 1 to 21)
- Oxygen saturation during walking training(day 1 to 21)
- perceived exertion for leg fatigue (Borg-scale)(during three weeks of rehabilitation)
- Sit-to-stand-test(day 1 to 21)
- fat free mass in kilogram(day 1 to 21)
- forced expiratory volume in 1 second (FEV1) in liter(day 1 to 21)
- 36 item short-form health Survey (SF-36)(day 1 to 21)
- chronic respiratory questionnaire (CRQ)(day 1 to 21)
- hospital anxiety and depression scale (HADS)(day 1 to 21)
研究者
Klaus Kenn
Head physican (department of pneumology)
Schön Klinik Berchtesgadener Land