Stress, Memory, and Rumination in Maltreated Adolescents
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 400
- 试验地点
- 2
- 主要终点
- Delarative recognition memory
研究概览
简要总结
Child maltreatment is one of the most formidable public health crises in the United States, affecting millions of youth each year. The adverse consequences of maltreatment for youth, as well as for their families and entire communities, are pervasive, costly, and enduring. To intervene and reduce these consequences, it is imperative that victims provide clear and accurate accounts of their prior experiences. Currently, considerable skepticism exists regarding maltreated youth's ability to provide such accounts, especially for experiences that were stressful, leading to youths' reports being challenged or not believed. It is possible that this skepticism is unwarranted, and maltreated youth actually demonstrate better memory than their non-maltreated counterparts, but only for stressful salient personal experiences. This project will ethically and rigorously test this possibility via a short-term longitudinal experimental investigation that compares the effects of acute stress on memory between maltreated and demographically matched non-maltreated 12-17-year-olds. In an initial in-person session, youth will be randomly assigned (equal maltreated and non-maltreated youth across age) to complete standardized salient personal activities that are experimentally manipulated to vary in whether they induce higher or lower levels of acute stress. Immediately afterward, youth will complete an encoding task comprised of positive, negative, and neutral images. In subsequent sessions (two remote and one in person) spanning approximately one month, youth's memory will be tested for the images via a recognition task asking them to discriminate previously seen from unseen images and for the personal activities via recall and direct questions that probe for the extent and accuracy of memory. Youth's rumination about the personal activities will also be measured. The project's main hypothesis is that maltreatment will lead to particularly robust memory for the personal activities, but only when the youth complete these under conditions of high stress. By contrast, because the emotional and neutral images are not personally meaningful, maltreatment is expected to constrain youth's memory performance for the images. It is also hypothesized that rumination will serve as an important mediator of the links between stress and memory for the higher stress personal activities, most notably in the maltreated youth. Overall, the project's results will provide much-needed knowledge about the precise ways that maltreatment shapes different facets of youth's memory, knowledge. This knowledge will be enormously valuable in improving trust in maltreated youth's reporting of stressful experiences and hence in directing interventions for victimized youth.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 12 Years 至 17 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ages 12-17 at start, half self reported or documented prior contact with social services/dependency court; half always lived with at least one biological parent
排除标准
- •Public speaking or math anxiety, cognitive impairments, head injuries, learning disabilities, steroid/hormonal treatments, or neuroendocrine diseases
结局指标
主要结局
Delarative recognition memory
时间窗: 10 days from first session
This memory measure reflects how well participants remember images that they encoded in Session 1. Participants are presented with previously seen and unseen images. Their job is to discriminate the two (i.e., say "old" for prior images and "new" for unseen images). Scores computed based on their responses include discriminability and response bias tendencies. These scores will be examined in relation to participants' maltreatment status and whether they encoded the images under high or low stress conditions.
Event Memory
时间窗: 30 days from first session
This memory measure reflects how well participants remember the entire first session, during which they had completed either the HS or LS TSST-M. Thus, of interest concerns differences in youth's memory for a stressful versus nonstressful prior salient experiences. Responses to recall and direct questions are coded for completeness and accuracy. These scores will be examined in relation to participants' maltreatment status and whether the original experience was higher versus lower stress.
次要结局
- State Rumination(10 days, 20 days, and 30 days from first session)
研究者
Jodi Quas
Professor
University of California, Irvine
