Fluid Status and Body Composition Analysis in Patients After Cardiac Surgery Assessed by Bioelectrical Impedance Method and Its Impact on Postoperative Morbidity and Mortality
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Fluid distribution during the early postoperative period (≤ 5 days)
研究概览
简要总结
Evaluation of fluid status in cardiac surgery patients using bioelectrical impedance and its impact on postoperative morbidity and mortality
详细描述
Hydration and fluid balance dynamics after cardiac surgery is complex and requires comprehensive knowledge of bluid balance dynamics. Surgical trauma, anaesthesia and use of cardiopulmonary bypass significantly influence postoperative fluid status. Deviations from normal values on the other hand can be related to increase in morbidity and mortality.
The purpose of this prospective observational clinical study is to assess fluid status using bioelectric impedance in patients undergoing cardiac surgery and to evaluate its impact on postoperative morbidity and mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Fluid distribution during the early postoperative period (≤ 5 days)
时间窗: Perioperative period (preoperatively, on the first, third, and fifth postoperative day)
Bioelectrical impedance vector analysis
次要结局
- Impact of fluid distribution/fluid overload on 30-day postoperative mortality(On day 30)
- Impact of fluid distribution/fluid overload on duration of postoperative mechanical ventilation(Duration of stay in ICU (estimated to up to 5 days))
- Impact of fluid distribution/fluid overload on length of stay in the intensive care unit(Duration of stay in ICU (estimated to up to 5 days))
- Impact of fluid distribution/fluid overload on 1-year postoperative mortality(At 1 year postoperatively)
- Impact of fluid distribution/fluid overload on postoperative complications (myocardial infarction, cardiogenic shock, vasoplegia, atrial fibrillation, heart failure, bleeding, infections, delirium)(Up to 1 year after the operation)
- Impact of fluid distribution/fluid overload on length of hospitalisation(Duration of hospital stay (up to 1 month))
研究者
Laura Kekec
Principal Investigator
University Medical Centre Ljubljana