POSTOPERATIVE ANALGESIC EFFECT OF INTRAPERITONEAL ROPIVACAINE WITH AND WITHOUT MAGNESIUM SULFATE IN LAPAROSCOPIC CHOLECYSTECTOMY-A PROSPECTIVE OBSERVATIONAL STUDY
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- To assess the
研究概览
简要总结
the study is to compare the duration of analgesia and incidence of pain after intraperitoneal instillation of ropivacaine with and without magnesium sulphate in patints undergoing elective laparoscopic cholecystectomy,secondarily the study aims to note the post drug instillation hemodynamics,incidence and severity of postoperative nausea and vomiting
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •PATIENTS WHO ARE ASA CLASS 1 OR 2 UNDERGOING ELECTIVE LAPROSCOPIC SURGERY BMI -18 TO 30.
排除标准
- •PATIENT WITH ECG SHOWING CONDUCTION ABNORMALITIES PREGNANT AND BREASTFEEDING PATIENT ON BETA BLOCKERS PATIENT WITH CHRONIC PAIN ON OPIOIDS AND OTHER ANALGESICS HISTORY OF ALLERGY TO STUDY DRUGS SURGERY DURATIONS MORE THAN THREE HOURS CONVERSION TO OPEN PROCEDURE EMERGENCY CHOLYCYSTECTOMY PATIENTS REQUIRING COMMON BILE DUCT EXPLORATION.
结局指标
主要结局
To assess the
时间窗: baseline,1 hour,2hour.6 hour,12 hour,24 hour
1.duration of analgesia after intraperitoneal instillation of ropivacaine with and without magnesium sulphate,
时间窗: baseline,1 hour,2hour.6 hour,12 hour,24 hour
3.total doses of rescue analgesics in each groups
时间窗: baseline,1 hour,2hour.6 hour,12 hour,24 hour
4.type of pain.
时间窗: baseline,1 hour,2hour.6 hour,12 hour,24 hour
2.Mean pain scores during 24 hour ,
时间窗: baseline,1 hour,2hour.6 hour,12 hour,24 hour
次要结局
- Secondary objective(To study the post instillation hemodynamic changes in terms of heart rate(HR), systolic blood pressure(SBP), diastolic blood pressure(DBP), Oxygen saturation (SpO2), End Tidal Co2 (EtCO2) and postoperative nausea and vomiting(PONV))