Validation of the use of Rayflow catheter in measuring absolute coronary flow in patients with severe aortic stenosis.

MonashHeart, Monash Medical Centre0 个研究点目标入组 10 人开始时间: 2022年6月28日最近更新: 2022年11月14日

适应症

试验速览

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•1)Age greater than or equal to 18yrs and less than or equal to 95yr old.
•2)Able to provide informed, written consent.
•3)Patients with no more that 30% visual stenosis in at least one coronary artery at time of coronary angiography.
•4)Patients presenting for a diagnostic angiogram for severe symptomatic aortic stenosis (mean gradient >=40mmHg or Vmax >=4m/s or DI <=0.25 on screening transthoracic echocardiogram

•1)Left ventricular ejection fraction <=30%
•2)Chronic renal impairment, as defined by estimated glomerular filtration rate <=30ml.min/1,73m2.
•3)Resting bradycardia, heart rate <=40 beats/min.
•4)Myocardial infarction within last three months.
•5)Previous coronary artery bypass surgery
•6)Unfavourable coronary anatomy that would prohibit safe guidewire passage.
•7)Women of childbearing age.
•8)Low flow low gradient aortic stenosis.
•9)History of asthma precluding use of adenosine.
•10)Persistent atrial fibrillation.
•11)Prior PCI to target vessel.

发起方

MonashHeart, Monash Medical Centre