Efficacy of Tendon Strip Injections compared to sham following failure of conservative therapy for Achilles tendinopathy

Monash University0 个研究点目标入组 192 人开始时间: 2019年10月22日最近更新: 2024年4月15日

适应症

试验速览

暂无简介。

•Previously trialled first line recommended treatment
•Aged 18 years or above
•more than 3 months of pain in the mid-portion Achilles area proximal to the Achilles
•tendon insertion in the calcaneum)
•Primary complaint of mid-portion Achilles pain on one or both lower limbs
•VISA-A <75 points
•Clinical diagnosis of mid-portion Achilles tendinopathy based on the following
•o Gradual onset pain in the relevant area;
•o Midportion Achilles pain during or after Achilles tendon loading activities (e.g. walking, running)
•Ankle joint examination, and especially passive plantar-flexion is essentially normal,
•Confirm diagnosis with ultrasound imaging of the Achilles tendon. One or more of the
•following features present in the mid-portion area: (i) hypoechoic regions; and/or (ii)
•Doppler signal indicative of vascularisation.

•Previous Achilles tendon surgery in the symptomatic lower limb(s)
•Previous Achilles tendon rupture in the symptomatic lower limb(s)
•Other ankle conditions including impingement syndrome, insertional Achilles tendinosis,
•Achilles paratenonitis without tendinopathy
•Tendinopathy caused by inflammatory conditions (e.g. ankylosing spondylitis)
•Neurological disorders (i.e. Parkinson’s syndrome, stroke)
•Inherited connective tissue disorders (i.e. Ehlers- Danlos syndrome, Marfan’s syndrome)
•Use of fluoroquinolone antibiotics within the previous two years
•Injection of local anaesthetic, corticosteroid, platelet rich plasma or other pharmaceutical agent into the Achilles tendon or surrounding area within the previous three months
•Any medical and/or social reason that, in the opinion of the investigators, makes the participant unsuitable for inclusion
•Serious mental health problem that would preclude adherence to study or treatment protocols
•Known allergies or hypersensitivity to the study drugs
•Needle phobia or a blood clotting disorder

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