NCT03466632Unknown3 期
Randomised Study Comparing the Use of Propofol Versus the Use of Dexmedetomidine as a Sedative Agent for Patients Presented for Lower Gastrointestinal Endoscopy
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Number of patients with adequate sedation
研究概览
简要总结
Dexmedetomidine as a Sedative Agent for Patients Presented for Lower Gastrointestinal Endoscopy
详细描述
Propofol Versus the Use of Dexmedetomidine as a Sedative Agent for Patients Presented for Lower Gastrointestinal Endoscopy
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 25 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 25-45 years,
- •ASA class I or II,
- •who are scheduled for elective outpatient colonoscopy
排除标准
- •refused to give informed consent
- •if they had known hypersensitivity to the used drugs
- •patients with morbidly obese patients
- •patients with increased risk for airway obstruction as obstructive sleep apnea,
- •Liver diseases
研究组 & 干预措施
• Propofol Group
Active Comparator
propofol 1.5 mg/kg slow intravenously, followed by maintenance dose of 0.5 mg/kg/h throughout the procedure..
干预措施: Propofol (Drug)
• Dexmedetomidine Group
Active Comparator
dexmedetomidine 1 ug/kg over 10 minutes as a bolus dose followed by continuous infusion at a dose of 0.5 ug/kg/h as maintenance dose throughout the procedure
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Number of patients with adequate sedation
时间窗: 6 months
the number of patients adequately sedated
次要结局
未报告次要终点
研究者
Sherief Abd-Elsalam
Principle investigator
Tanta University
研究点 (1)
Loading locations...
相似试验
Unknown
4 期
Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in CirrhoticsHepatic EncephalopathyNCT01356121Govind Ballabh Pant Hospital120
Unknown
不适用
Dexmedetomidine for Sedation Undergoing BronchoscopySafety IssuesNCT04169685Kaohsiung Medical University80
已完成
4 期
Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal IntubationSedationIntubationNCT04753515Sixth Affiliated Hospital, Sun Yat-sen University100
已完成
2 期
Propofol vs. Midazolam With Propofol for Sedative Endoscopy in Patients With Previous Paradoxical Reaction to MidazolamSedationEndoscopyNCT04072328DongGuk University30
尚未招募
不适用
Comparing two medicines for putting a tube in the windpipe for breathing in patients whose mouth does not open fullyCTRI/2020/03/023678Rajiv Gandhi Cancer Institute and Research Centre