NCT03100357Unknown不适用
Changes in Esophageal Motility and Swallowing Symptoms After Thyroid Surgery - a Prospective Cohort Study
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 39
- 主要终点
- Motility disturbances
研究概览
简要总结
The pronounced effect of goiter on the esophagus needs further exploration, as the mechanisms by which goiter leads to swallowing difficulties are unknown. By investigating esophageal motility using high resolution esophageal manometry before and after thyroidectomy we seek to examine the impact of the goiter mass on the esophagus and swallowing with six months follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with symptomatic benign nodular goiter referred for thyroidectomy
排除标准
- •Previous surgery to the neck;
- •Suspicion of thyroid cancer
- •Age below 20 years or above 80 years
- •Neuromuscular disease.
结局指标
主要结局
Motility disturbances
时间窗: Before and six months following thyroidectomy
Change in number of failed swallowings from baseline
次要结局
未报告次要终点
研究者
Jesper Roed Sorensen
MD PhD fellow
University of Southern Denmark
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