NCT00360048已完成不适用
Oxytocin Effects on Cytokines and Endocrine Parameters After LPS Induced Systemic Inflammatory Effects in Healthy Volunteers
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- TNF-alpha
研究概览
简要总结
The aim of this study is to determine if oxytocin administration is able to blunt LPS induced increase of cytokines (TNF-α) and if there is a change in the endocrine response after lipopolysaccharide administration in humans.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Men aged 18 years or older with no disease history
- •Written informed consent
排除标准
- •Receiving any medication
- •Probands who suffer from infectious disease
结局指标
主要结局
TNF-alpha
时间窗: six hours
次要结局
- ACTH, cortisol, procalcitonin, IL-1ra, IL-4, IL-6, MIP-1alpha, MIP-1 beta, MCP-1, IP-10, VEGF, body temperature, BNP, Ghrelin,(six hours)
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
1 期
The Moderating Role of Baseline Oxytocin on Its Psychotherapy-facilitating Effects Among Patients With Eating DisordersEating DisordersNCT05865288Shalvata Mental Health Center90
招募中
不适用
Oxytocin Effects on Self Versus Other TouchHealthyNCT05899517University of Electronic Science and Technology of China40
已完成
不适用
How does oxytocin affect brain functioning in people at high risk of developing psychosis?Schizophrenia, schizotypal and delusional disordersMental and Behavioural DisordersISRCTN48799530King's College London30
已完成
2 期
Evaluation of Oxytocin,s effect in comparison with placebo on craving; withdrawal and stress response due to heroin.Condition 1: Withdrawal syndrome. Condition 2: Craving.Mental and behavioural disorders due to use of opioidsIRCT2015103024792N1Vice chancellor for research Kashan University of Medical Sciences50
已完成
4 期
Continued Versus Discontinued Oxytocin Stimulation of LabourAdverse Reaction to OxytocinNCT02553226University of Aarhus1,200