Effect of milk fortified with plant sterols on the lipid profile and serum non-cholesterol sterols of patients with moderate hypercholesterolemia: A randomised, crossover feeding study

nilever R&D (Netherlands)0 个研究点目标入组 50 人开始时间: 2010年10月7日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Men and women with moderate hypercholesterolemia
•2. Aged between 18 and 75 years
•3. Body mass index (BMI) <31 kg/m2
•4. Serum total cholesterol between 4.91 and 7.75 mmol/L
•5. Low Density Lipoprotein (LDL) cholesterol >3.36 mmol/L
•6. Triglycerides <3.39 mmol/L
•7. Participants can be under stable lipid-lowering drug treatment (statins or fibrates, statins at doses of no more than simvastatin 40 mg/day or equivalent) or cardiac medication in patients with previous cardiovascular disease
•8. Written informed consent. Participants were given a leaflet with explanation of the study, including reasons for masking the contents of the milk product, and information on how to contact investigators if necessary.

•1. Subjects on a weight-losing diet
•2. Familial hypercholesterolemia
•3. Established type 2 diabetes
•4. Lactose intolerance
•5. Consumption of products that can influence cholesterol metabolism (other than statins and fibrates), such as
•5.1. resins
•5.2. ezetimibe
•5.3. psyllium products
•5.4. fish oil products
•5.5. soya lecithin
•5.6 phytoestrogens

发起方

nilever R&D (Netherlands)