The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S): A Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Appendicular skeletal muscle mass index (ASMI)
研究概览
简要总结
Sarcopenia prevention and management are highly prioritised goals in the Healthy Ageing agenda. The study aims to: 1) evaluate the effects of the digital-enhanced, volunteer-engaged collaborative care pathway to improve sarcopenia, reduce fall risk, and increase health-related quality of life (HRQL) among community-dwelling older adults with risk of, or diagnosed with, sarcopenia; 2) evaluate whether the volunteers who received health coach capacity training and supported the intervention experienced health benefits across time; 3) explore the engagement experiences and perceived effects of elderly participants with sarcopenia during the program; 4) evaluate the intervention implementation process and effects from the perspectives of social care workers.
详细描述
Sarcopenia-an age-related, progressive syndrome characterised by reduced skeletal muscle strength and mass/quality with impaired physical performance-has become a key modifiable determinant of frailty, falls, disability, hospitalisation, and mortality among community-dwelling older adults. In Hong Kong, approximately 9% of adults aged 65 and above are diagnosed with sarcopenia, indicating a substantial community burden. Beyond functional loss, sarcopenia is associated with increased healthcare utilisation and costs, evidence suggests higher risks of hospital admission and longer length of stay among older adults with sarcopenia, contributing to considerable economic impact.
A key gap in sarcopenia management: many interventions and service models have limited capacity to sustain lifestyle behavioural changes over time.
To address the above gaps, the VELO-S project proposes a 12-week, volunteer-engaged lifestyle optimisation programme grounded in WHO ICOPE and delivered through an ICOPE-based critical pathway for nutrition and exercise. VELO-S is enabled by a digital platform that contains an exhaustive checklist of person-centred risk factors and corresponding, precise lifestyle activity recommendations for each care pathway (nutrition and physical activity). In parallel, VELO-S incorporates goal-oriented empowerment and volunteer-enhanced interactive lifestyle empowerment workshops, targeting the sustainability mechanisms required to deter sarcopenia progression in community-dwelling older adults.
This overall study aims to evaluate the effects and implementation of VELO-S among community-dwelling older adults with pseudo-sarcopenia or sarcopenia.
The objectives of this study are to (1) examine the effectiveness of a 12-week VELO-S intervention compared to an attention control in improving appendicular skeletal muscle mass, handgrip strength, physical mobility function, risk of sarcopenia, frailty, nutrition, physical activity, and health-related quality of life among community-dwelling older adults with sarcopenia risk or sarcopenia at 12 weeks post-intervention and 24 weeks follow-up; (2) to examine changes in health-related quality of life and mental health among volunteers who participated in the health coach capacity training at 12 weeks post-intervention delivery and 24 weeks follow-up, compared to baseline; (3) to explore the engagement experiences and perceived effects of elderly participants with sarcopenia during the program; (4) to explore the perspectives of social care workers on their experience on intervention effects and implementation process.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessors will be blinded to the intervention assignment results.
入排标准
- 年龄范围
- 60 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •aged 60 or above
- •Pseudo-Sarcopenia as indicated by a score on SARC-CaIF ≥11, OR sarcopenia according relative BIA-based appendicular skeletal mass/ height (Men: <7 kg/m2; women: <5.7 kg/m2), OR handgrip strength on dominant hand (male <28 kg, female <18 kg) (Chen et al., 2025)
- •the ability to use a smartphone, electronic tablet, or computer
- •consent to participate
排除标准
- •having medical conditions contradictory to physical activity including unstable cardiovascular and orthopaedic conditions
- •engaging in other structured health promotion program involving physical activity and nutritional enhancement
研究组 & 干预措施
Attention control
To control for the non-specific effects of receiving attention and social interaction on outcomes, participants in the attention control group will receive an education protocol that is unrelated to sarcoepnia, with comparable duration and frequency of contact and engagement to those in the intervention group ensuring comparable exposure to social engagement and attention. Educational materials will be distributed to participants.
干预措施: Attention control (Behavioral)
Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S)
This digital program incorporates a 12-week, volunteer-engaged lifestyle optimisation programme grounded in WHO ICOPE and delivered through an ICOPE-based critical pathway for nutrition and exercise.
干预措施: Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S) (Behavioral)
结局指标
主要结局
Appendicular skeletal muscle mass index (ASMI)
时间窗: Baseline (T0), 3 months (T1), and 6 months (T2)
Appendicular skeletal muscle mass index (ASMI) measured by Bioelectrical impedance analysis (BIA)
Handgrip Strength
时间窗: Baseline (T0), 3 months (T1), and 6 months (T2)
Handgrip strength will be measured by a hydraulic hand dynamometer from dominant hand, taking the highest value among 3 measurements. Low muscle strength is defined if male \<28kg, and femal \<18kg.
Short Physical Performance Battery (SPPB)
时间窗: baseline (T0), 3 months (T1), and 3 months (T2)
Physical function will be measured by the Short Physical Performance Battery (SPPB), which combines balance test, gait velocity and chair stand. SPPB score ranges from 0-12, higher score better physical performance. Low physical function is defined by SPPB score ≤9.
次要结局
- Sarcopenia and calf circumference scale (SARC-CalF)(Baseline (T0), 3 months (T1), and 6 months (T2))
- 11-item Edmonton Frail Scale(Baseline (T0), 3 months (T1), and 6 months (T2))
- Timed Up and Go (TUG) test(Baseline (T0), 3 months (T1), and 6 months (T2))
- The Mini Nutritional Assessment (MNA)(Baseline (T0), 3 months (T1), and 6 months (T2))
- International Physical Activity Questionnaire (IPAQ-Short)(Baseline (T0), 3 months (T1), and 6 months (T2))
- Sleep duration(Baseline (T0), 3 months (T1), and 6 months (T2))
- The EuroQoL-5D-5L instruments(Baseline (T0), 3 months (T1), and 6 months (T2))
研究者
Prof. Yu, Doris Sau Fung
Professor
The University of Hong Kong
