Establishing the Central and Peripheral Fatigue Indexes and VR Based Anti-fatigue Training Paradigm for Individuals With Parkinson Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 31
- 试验地点
- 2
- 主要终点
- Muscle twitch force
研究概览
简要总结
Fatigue is one of the most common symptoms in individuals with Parkinson's Disease (PD). Past researches indicated that more than half of the individuals with PD demonstrated fatigue symptom. The severity of fatigue was also correlated to the quality of life in individuals with PD. Finding the contributions of the central and the peripheral factors to fatigue, building reliable fatigue indexes, and developing an effective training program for individuals with PD are very important.
The purpose of this project is to develop non-invasive method to monitor central and peripheral fatigue, to establish Virtual Reality(VR) anti-fatigue ergo cycling training paradigm, and to evaluate the long term training effect in individuals with PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of Parkinson disease
- •Hoehn and Yahr ≦3
排除标准
- •Musculoskeletal injuries
- •Osteoporosis
- •Any peripheral or central nervous system injury or disease patients
结局指标
主要结局
Muscle twitch force
时间窗: baseline, 1 week
Measure of changes in muscle twitch force by interpolation twitch technique.
Muscle voluntary activity level
时间窗: Baseline,1 week
Measure of changes in muscle voluntary activity level by interpolation twitch technique.
Heart rate/Heart rate variability
时间窗: Baseline,1 week
Measure of changes in Heart rate/Heart rate variability.
Borg's rate of perceived exertion
时间窗: Baseline,1 week
Measure of changes in Borg's rate of perceived exertion.
次要结局
未报告次要终点
研究者
Ya-Ju Chang
Profesor
Chang Gung University