One-Puncture Versus Multipoint Technique of Rectus Sheath Block With Transverse Abdominis Plane Block for Analgesia After Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- The total postoperative opioid consumption in the first 24 hours.
研究概览
简要总结
the purpose of this study is to compare of better postoperative analgesia following laparoscopic cholecystectomy using either one puncture rectus sheath block with transverse abdominis plane block or multipoint technique
详细描述
after being informed about the study and potential risks. All patients giving written consent will be randomized by double blind manner into 3 groups each one containing 34In the One puncture "O" group (n= 34): The patient will receive one-puncture technique of RSB combined with TAPB.
In the Multipoint "M " group (n= 34): The patient will receive multipoint technique of RSB combined with TAPB.
In the Control "C " group (n=34 ): The patient will receive patient controlled analgesia&;PCA&
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18-45 years old.
- •Sex: both sexes.
- •Physical status: ASA I to III.
- •Body mass index (BMI): 18- 30 kg/m
- •Type of operations: elective laparoscopic cholecystectomy.
- •Written informed consent from the patient.
排除标准
- •Known hypersensitivity to lidocaine or bupivacaine.
- •Opioid-dependent patients.
- •Coagulation disorders or taking drugs affect surgical hemostasis.
- •Patients with pre-existing neurological deficits.
- •Uncooperative patient or with altered mental status.
研究组 & 干预措施
one puncture
one-puncture technique of RSB combined with TAPB.
干预措施: US-guided RSB and TAPB by one-puncture technique. (Procedure)
Multipoint
multipoint technique of RSB combined with TAPB.
干预措施: multipont (Procedure)
control
nalbuphine (2 mg/kg) and normal saline to a total volume of 150 mL, with a background infusion rate of 2 mL/h, a bolus dose of 2 mL, a lockout interval of 15 min, and a maximum limit of 10 mL within 1 h.
结局指标
主要结局
The total postoperative opioid consumption in the first 24 hours.
时间窗: 24 hours postoperative
opioid consumption
次要结局
- The block performance time(up to 5 minutes)
- Onset of sensory block(up to 30 minutes)
- The Numerical Pain Rating Scale(24 hours postoperative)
- Patient satisfaction(24 hour postoperative)
研究者
Marwa Mohamed Medhat
assistant professor of anesthesia and surgical intensive care (Principal Investigator)
Zagazig University