NL-OMON50039已完成不适用
Endogenous Glucose Production in Subjects with Glycogen Storage Disease Type Ia estimated by a single oral dose of stable isotopes: an investigator-initiated human pilot study. - ENGLUPRO GSDIa: Endogenous glucose production in GSDIa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 12 至 99（—）
入选标准
- •In order to be eligible to participate in this study, The GSDIa patients must
- •meet all of the following criteria:
- •The diagnosis should be confirmed by G6PC mutation analysis
- •Age above 16 years
- •Stable medical condition before the start of the test procedures
排除标准
- •A potential GSD Ia patient who meets any of the following criteria will be
- •excluded from participation in this study:
- •Age < 16 years
- •Recent (< 1 month) history of hospitalization due to hypoglycaemia
- •Intercurrent illness, defined as (a combination of) decreased dietary intake,
- •vomiting, diarrhoea and fever (>38.5*C) in the week prior to the visit
- •Pregnancy
- •A potential age and gender-matched healthy participant who meets any of the
- •following criteria will be excluded from participation in this study:
- •Confirmed diagnosis or history suggestive of diabetes mellitus
- •First grade family member with a confirmed diagnosis associated with fasting
- •intolerance
- •History suggestive of fasting intolerance
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