跳至主要内容
临床试验/NCT05412303
NCT05412303已完成不适用

Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock.

Centre Hospitalier Universitaire Dijon2 个研究点 分布在 1 个国家目标入组 2,769 人开始时间: 2019年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
2,769
试验地点
2
主要终点
Pourcentage of death

研究概览

简要总结

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a well-established lifesaving treatment for refractory cardiogenic shock, with or without concomitant respiratory failure. VA-ECMO is usually started in presence of refractory low cardiac output syndrome following CPB weaning. Currently, there is no consensus about the best timing for implantation and initiation of VA-ECMO in this setting. Some publications have suggested that VIS score could be used to determine the necessity of VA-ECMO in cardiologic area. It was demonstrated that a VIS score between 20 and 40 may be a cut-off value to discuss the implantation of VA-ECMO. Post cardiotomy shock is a very interesting setting because the timing of cardiogenic shock is known and several bias are more controlled than in medical area.

Based on the well-established ability of VIS Score in predicting mortality, we will investigate the role of the VIS Score as a determinant for early VA-ECMO implantation in patients suffering of post-cardiotomy cardiogenic shock.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age over 18 years
  • Cardiac surgery with cardiopulmonary bypass
  • Post cardiotomy cardiogenic shock
  • ECMO-VA implanted in OR

排除标准

  • Heart transplantation
  • Incomplete data in relation to outcomes
  • Cardiac arrest

结局指标

主要结局

Pourcentage of death

时间窗: Day 30

次要结局

  • 1 - Number of complications(Day 30)
  • 3 - number of days in hospital(through study completion, up to 3 months)
  • 2 - number of days in intensive care(through study completion, up to 15 days)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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