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临床试验/NCT01530035
NCT01530035已完成不适用

Cardiovascular and Muscular Adaptations to Recreational Soccer and Strength Training in Elderly Healthy 65-75-year-old Men

University of Copenhagen2 个研究点 分布在 1 个国家目标入组 41 人开始时间: 2011年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
41
试验地点
2
主要终点
cardiac adaptations

研究概览

简要总结

A one-year intervention study of 41 healthy elderly men aged 65-75-years.Of these, 24 subjects are untrained men with no regular training activity for the last 5 years. After medical screening and pre-testing, they will be randomized into a football group (n=9), a strength-training group (n=9) or a sedentary control group (n=6). Additional 17 subjects are recruited from local football clubs and have been active football players for the last 40 years. Training will be performed 3x1 hour per week and evaluation will take place after 0, 3 and 12 months. Primary endpoints will be changes in cardiac and vascular structure and function measured by advanced echocardiography (tissue Doppler and speckle tracking imaging), and peripheral arterial tonometry (Endo---PAT device). Secondary endpoints will be evaluation of potential changes in VO2 max, blood pressure, muscle capillaries, lipid profile, circulating catecholamines, body composition, and insulin resistance.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
65 Years 至 75 Years(Older Adult)
性别
Male
接受健康志愿者

入选标准

  • 65-75 year old men
  • non-smoking
  • non-hypertension
  • non- cardiac disease

排除标准

  • cardiac disease
  • biomechanical disorders
  • cardiac medication

结局指标

主要结局

cardiac adaptations

时间窗: after 16 weeks and one year

changes in cardiac function after 16 weeks and one year measured by advanced echocardiography (tissue Doppler and speckle tracking imaging)

次要结局

  • Cardiorespiratory fitness, muscular adaptations, Bloodpressure and Glucose tolerance(after 16 weeks and one year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jakob Friis Schmidt

MD PhD student

University of Copenhagen

研究点 (2)

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