NCT02574039已完成不适用
Absorption, Metabolism and Excretion of Oat Phenolic Acids in Healthy Men.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 7
- 试验地点
- 2
- 主要终点
- Change from baseline in phenolic acid metabolite excretion
研究概览
简要总结
A diet rich in whole grain is inversely associated with cardiovascular disease risk and this benefit could be partly attributed to the phenolic acid content of whole grains. The exact absorption, metabolism and excretion of whole grain phenolic acids, however, is not fully understood. In a small human intervention trial, the investigators will investigate to what extent phenolic acids from whole grain oats are absorbed, excreted in urine and how they are metabolised.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 25 Years 至 65 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •25 to 65 years old
排除标准
- •Allergies to oats
- •Parallel participation in another research project
- •Having flu vaccination or antibiotics within 3 months of trial start
- •Taking food supplements within 3 months of trial start
- •Past or existing medical history of vascular disease, diabetes, hepatic, renal, gastrointestinal, haematological, neurological, thyroidal disease or cancer
结局指标
主要结局
Change from baseline in phenolic acid metabolite excretion
时间窗: Baseline and 48 hours
次要结局
未报告次要终点
研究者
Jeremy Paul Edward Spencer
Professor
University of Reading
研究点 (2)
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