Efficacy of Sodium Oxybate to promote sleep in the ICU: A randomized controlled trial

eiden University Medical Center0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•Admission to the ICU/MCU;
•Expected duration of ICU/MCU admission > 2 nights after detection of sleep difficulties;
•Awake, conscious (patients can be intubated);
•RASS (Richmond Agitation-Sedation Scale) score = -2;
•The patient is experiencing sleep difficulties based on their own or clinical judgment as well as on a low score (<60% average score) on the Richard Campbell Sleep Questionnaire;
•The ICU physician intends to prescribe general sleep promoting measures as well as a benzodiazepine because of the sleep problems.

•Use of sedatives for sleep problems (for example benzodiazepine use) in the last 3 days, except a low dose of Sufentanil (up to 2,5 µg/hr) in intubated patients since this dose is frequently needed to counteract laryngeal tube irritation;
•Current use of haloperidol, except a maintenance dose in patients recovering from a delirium;
•RASS score < -2;
•Active delirium, as assessed by a ICDSC-NL score > 3;
•SSADH-deficiency;
•Severe depression;
•Planned ICU admission time < 3 nights after detection of sleep difficulties.

发起方

eiden University Medical Center