Effect of Transcutaneous Electrical Acupoint Stimulation(TEAS) on the Hepatic and Renal Function Impaired by Pneumoperitoneum: a Prospective, Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 168
- 试验地点
- 1
- 主要终点
- Incidence of renal or hepatic dysfunction
研究概览
简要总结
The purpose of this study is to compare the effect of TEAS pretreatment and treatment on hepatic and renal dysfunction induced by pneumoperitoneum in patients undergoing laparoscopic surgeries.
详细描述
Patients were randomly assigned to three groups, control group and two intervention groups, receiving TEAS before and after general anesthesia induction respectively. TEAS was given through electrodes attached to acupoints. The time for TEAS was 30min. Venous blood samples were collected before and 20min after pneumoperitoneum. Hepatic and renal function index including AST, ALT, ALP, BUN, Cr were measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age>18yrs,<60yrs；
- •Scheduled for laparoscopic surgery under general anesthesia；
- •Informed consented
排除标准
- •Patients with hepatic or renal dysfunction；
- •Patients with severe hypertension or cardiac dysfunction；
- •Patients with severe pulmonary disease；
- •Patients with hemoglobin<100g/L
研究组 & 干预措施
Control
Patients were given no TEAS
TEAS Pretreatment
Patients were given 30min of TEAS before pneumoperitoneum
干预措施: TEAS pretreatment (Other)
TEAS Treatment
Patients were given 30min of TEAS during pneumoperitoneum
干预措施: TEAS treatment (Other)
结局指标
主要结局
Incidence of renal or hepatic dysfunction
时间窗: 20min after pneumoperitoneum
percentage of patients with renal or hepatic dysfunction
次要结局
- Change of hepatic function(20min after pneumoperitoneum)
- Change of renal function(20min after pneumoperitoneum)
研究者
Zhihong LU
Dr.
Air Force Military Medical University, China