ITMCTR2026001735进行中（未招募）Unknown
A Study on the Effects and Mechanisms of Acupuncture in Modulating "Peripheral-Central" Sensitization in Gastroesophageal Reflux Disease via the TRPV1/NMDAR Pathway
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Affiliated to Shanghai University of Traditional Chinese Medicine0 个研究点开始时间: 2026年7月15日最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 75（—）
- 性别
- All
入选标准
- •(1) Age = 18 and = 75 years; No gender perference;
- •(2) Meets the diagnostic criteria for gastroesophageal reflux disease (GERD): presence of typical heartburn and/or reflux symptoms lasting = 3 months; Gastroesophageal Reflux Disease Questionnaire (GERDQ) score =
- •Or, within the past year, have been diagnosed with reflux esophagitis (Los Angeles [LA] grade A or higher) via upper gastrointestinal endoscopy, or have been confirmed to have pathological reflux via 24-hour esophageal pH-impedance monitoring;
- •(3) Be mentally alert and lucid, able to correctly understand the questionnaire assessment, and capable of completing the questionnaire independently;
- •(4) Understand and agree to participate in this study and sign the informed consent form.
排除标准
- •(1) Gastroscopy reveals Barrett's esophagus, hiatal hernia, esophageal cancer, or severe esophageal erosion (LA grade C/D);
- •(2) History of esophageal or gastric surgery;
- •(3) At the time of enrollment, patients with relatively severe underlying diseases of the cardiovascular, cerebrovascular, hepatic, renal, endocrine, hematological, or neuropsychiatric systems, or a tendency to bleed;
- •(4) Pregnant or breastfeeding women, or women currently planning to become pregnant;
- •(5) Patients currently participating in other clinical trials involving drugs or medical devices;
- •(6) Patients with an allergy to acupuncture or who experience psychological anxiety that prevents them from cooperating with this treatment.
研究者
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