NCT00988299已完成不适用
Energy Expenditure Responses to Acute Exercise in Older Women
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- non-exercise activity calorie expenditure
研究概览
简要总结
In older, normal-weight women (60-75 yrs, BMI=18-28 kg/m2), an acute bout of higher-intensity (60% of maximum effort) aerobic exercise, in comparison to an isocaloric bout of lower-intensity (45% of maximum effort) exercise (caloric expenditure of 3.5 kcal/kg body weight for both), will result in differential:
- decline in non-exercise activity calorie expenditure in the subsequent 48 hours after exercise;
- increase in resting metabolic rate 48 hours after exercise;
- increase in serum free triiodo-L-thyronine (free T3) concentrations immediately following exercise;
- decline from pre-exercise in plasma leptin and serum free T3 concentrations 48 hours after exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age 60-75 years
- •normal weight
- •Weight-stable (± 5%) within the previous 3 months
- •Non-smoking for last year
- •Able to provide own transportation to study visits
- •Not currently involved in any other research study
- •Willing and able to participate in all aspects of the trial including research testing
- •Willing to give informed consent to participate
排除标准
- •Self-reported significant cardiovascular disease
- •Other self-reported medical conditions such as diabetes, chronic or recurrent respiratory conditions, active cancer, musculoskeletal disease
- •Medications known to affect exercise performance or metabolism
- •Excess caffeine use (> 500mg/day)
- •Any self-reported contraindications to exercise
- •Clinical depression
- •Abnormal cognitive function -
结局指标
主要结局
non-exercise activity calorie expenditure
时间窗: 2 days after exercise sessions
次要结局
- resting metabolic rate(2 days after exercise sessions)
研究者
研究点 (2)
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