Effects of Resistance Exercise Volume on the Variability of the Hypertrophic Response in Elderly
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 102
- 试验地点
- 1
- 主要终点
- Quadriceps muscle cross-sectional area
研究概览
简要总结
The study aimed to investigate the effects of resistance training volume manipulation on whole muscle hypertrophy among non-responders and responders to a low resistance training dose (single-set).
详细描述
The magnitude of muscle hypertrophy in response to resistance training (RT) is highly variable between individuals (response heterogeneity). Manipulations in RT variables may modulate RT-related response heterogeneity; yet, this remains to be determined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •60 years and older
- •not engaged in regular resistance and/or aerobic training for at least six months before the intervention
排除标准
- •diagnosed type I diabetes mellitus
- •arrhythmia
- •noncontrolled hypertension
- •any major orthopedic musculoskeletal condition
- •use of any dietary supplement or drug with potential anabolic effects
研究组 & 干预措施
Single set
One set of unilateral knee-extension exercise of 8-15 RM with a 60-90 s interval.
干预措施: Lower body resistance training (Other)
Four sets
Four sets of unilateral knee-extension exercise of 8-15 RM with a 60-90 s interval between sets.
干预措施: Lower body resistance training (Other)
结局指标
主要结局
Quadriceps muscle cross-sectional area
时间窗: 10 weeks
Quadriceps muscle CSA was obtained through magnetic resonance imaging.
次要结局
- Maximum dynamic strength(10 weeks)
研究者
Hamilton Augusto Roschel da Silva
Principal Investigator
University of Sao Paulo