The Effects of Antioxidant Supplementation on Multiple Endurance Race Performance, Physiology, and Recovery.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Changes in Perceived Recovery Status (PRS)
研究概览
简要总结
Thirty active male and female athletes will be recruited for the study. Subjects will be examined at baseline for VO2max performance. Subjects will then be stratified and randomly divided equally (50% - 50%) into an Oceanix (supplemental) or placebo condition such that baseline VO2max match. Once randomization, subjects will be baseline tested for multiple measures of muscle force capacity, muscle soreness, immune function, and endocrine function. Upon completion of baseline testing, subjects will all complete a one-day, cross-training course in Tampa, Florida. The training course is known to be extremely vigorous and causes significant muscle damage. Subjects will then be retested for muscle function at 24, and 48 hours following the course. At 24- and 48-hours subjects will be asked to repeat a simulated time trial race. In this way, we will measure repeated race performance, recovery from intense exercise, muscle damage from exercise, and immune function during multiple races.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females age 18 to 45 years old
- •At least one year of cross training experience (i.e. 3 days/week)
排除标准
- •BMI of 30 or more kg/m²
- •Any allergies to fish, shellfish, algae, or seaweed are excluded from participation
- •Have any cardiovascular, metabolic, or endocrine disease
- •Undergone surgery that affects digestion and absorption
- •Drink heavily (> 7 and > 14 drinks per week for women and men, respectively)
- •Women who are pregnant or planning to be pregnant
- •Taking medication to control blood pressure, lipids, and blood glucose
- •Have taken or currently taking anabolic-androgenic steroids
结局指标
主要结局
Changes in Perceived Recovery Status (PRS)
时间窗: Baseline, 1 Day of Cross-Training Course, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Assessed through a visual analog scale (modified Borg Scale) numbered 0 to 10 with visual descriptors.
Changes in Perceived Soreness Scale
时间窗: Baseline, 1 Day of Cross-Training Course, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Assessed through a visual analog scale numbered 0 to 10 with visual descriptors.
Changes in Rating of Perceived Exertion (RPE)
时间窗: Baseline, 1 Day of Cross-Training Course, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Assessed through a visual analog scale numbered 0 to 10 with visual descriptors.
Changes in muscle strength
时间窗: Baseline, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Assessed by isometric mid-thigh pull.
Changes in One(1) Mile Timed Run
时间窗: Baseline, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Experimental outcome assessing how quickly a 1 mile run can be completed.
Changes in muscle power
时间窗: Baseline, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.
Assessed through ground reaction forces during countermovement and squat jumps on a force plate.
次要结局
- Creatine Kinase(Baseline, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.)
- Cortisol(Baseline, 24-Hour Post Cross-Training Course, 48-Hours Post Cross-Training Course.)