Assessment of Anti-aging Efficacy of Marine Collagen Peptides
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- The change of skin hydation
研究概览
简要总结
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged above 18 years old
排除标准
- •Subjects who are not volunteers
- •Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure
- •Subjects who have known cosmetic, drug or food allergies.
- •Patients are taking medicine for chronic diseases
- •Subjects receiving treaments for scalp, hair transplant, and other scalp medical care in past 12 weeks.
- •Subjects getting a manicure and perm in past 12 weeks.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Subjects receiving facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 12 weeks.
- •Students who are currently taking courses taught by the principal investigator of this trial.
- •Subjects are not willing to reveal the results of pictures after taking the product
- •Vegetarian.
结局指标
主要结局
The change of skin hydation
时间窗: Change from Baseline skin skin hydation at 12 weeks
Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.
The change of skin wrinkles
时间窗: Change from Baseline skin wrinkles at 12 weeks
VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles
The change of skin elasticity
时间窗: Change from Baseline skin elasticity at 12 weeks
Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.
The change of skin collagen density
时间窗: Change from Baseline skin collagen density at 12 weeks
DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units
The change of thumbs nail color
时间窗: Change from Baseline thumbs nail color at 12 weeks
Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L\* index
The degree of nails fragility
时间窗: Change from Baseline nails fragility at 12 weeks
Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.
The change of hair follicle strength
时间窗: Change from Baseline hair follicle strength at 12 weeks
Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair
The change of hair loss amount
时间窗: Change from Baseline hair loss amount at 12 weeks
Collect and measure the weight of loss hair. Units: gram
The change of hair density
时间窗: Change from Baseline hair density at 12 weeks
Soft Plus was utilized to picture and observe hair density.
The change of hair diameters
时间窗: Change from Baseline hair diameters at 12 weeks
Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter
The change of hair roots diameters
时间窗: Change from Baseline hair roots diameters at 12 weeks
Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter
The change of nails appearence
时间窗: Change from Baseline nails appearence at 12 weeks
Picture taken was utilized to record and observe nails appearence.
The change of nails growth
时间窗: Change from Baseline marking position at 12 weeks
Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter
次要结局
- The change of self-assessment skin, hair, and nails condition(Change from Baseline skin, hair, and nails condition at 12 weeks)