Efficacy Testing of Collagen Peptide Drink
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- The change of skin elasticity
研究概览
简要总结
To assess Collagen Peptide Drink on skin condition improvement
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged above 20 years old
排除标准
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
- •Constant drug use
- •Participated cosmetic product human study in the past 3 months.
结局指标
主要结局
The change of skin elasticity
时间窗: Change from Baseline skin elasticity at 4 weeks
Soft Plus was utilized to measure skin elasticity. Units: arbitrary units
The change of MMP-1 of blood
时间窗: Change from Baseline MMP-1 at 4 weeks
Venous blood was sampled to measure MMP-1
The change of TIMP-1 of blood
时间窗: Change from Baseline TIMP-1 at 4 weeks
Venous blood was sampled to measure TIMP-1
The change of skin wrinkles
时间窗: Change from Baseline skin wrinkles at 4 weeks
VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin texture
时间窗: Change from Baseline skin texture at 4 weeks
VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density
时间窗: Change from Baseline skin collagen density at 4 weeks
DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units
次要结局
- The change of skin UV spots(Change from Baseline skin UV spots at 4 weeks)
- The change of skin L* value(Change from Baseline L* value at 4 weeks)
- The change of skin brown spots(Change from Baseline skin brown spots at 4 weeks)
- The change of MDA of blood(Change from Baseline MDA at 4 weeks)
- The change of skin melanin index(Change from Baseline skin melanin index at 4 weeks)
- The change of skin spots(Change from Baseline skin spots at 4 weeks)
- The change of TNF-α of blood(Change from Baseline TNF-α at 4 weeks)
- The change of SOD-RBC of blood(Change from Baseline SOD-RBC at 4 weeks)
- The change of skin moisture(Change from Baseline skin moisture at 4 weeks)
- The change of blood total antioxidant capacity (TAC)(Change from Baseline TAC at 4 weeks)
- The change of IL-10 of blood(Change from Baseline IL-10 at 4 weeks)
- The change of f-thiols of blood(Change from Baseline f-thiols at 4 weeks)
- The change of t-GSH of blood(Change from Baseline t-GSH at 4 weeks)
- The change of GST-RBC of blood(Change from Baseline GST-RBC at 4 weeks)