Efficacy Evaluation of Collagen Drink Products

Not Applicable

Completed

• Conditions: Skin Condition
• Interventions: Dietary Supplement: MAXI Collagen drink; Dietary Supplement: Placebo drink; Dietary Supplement: Normal fish collagen drink

• Registration Number: NCT06194487
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess MAXI Collagen drink on skin condition improvement

Detailed Description

Not available

Study Timeline

• Study Start: 2023-10-01
• Study First Submitted: 2023-12-22
• Study First Submitted QC: 2023-12-22
• Primary Completion: 2023-12-29
• Study First Posted: 2024-01-08
• Study Completion: 2024-01-26
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-03
• Last Update Posted: 2024-05-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• Healthy adults aged 35-65 years old

Exclusion Criteria

• Subject with skin surface damage larger than $50 coin area.
• Subject who had skin allergies caused by diet or undrwent cosmetic or medical treatment within 6 months.
• Subject who is a vegetarian and allergic to seafood, alcohol or listed ingredients in the product.
• Students who are currently taking courses taught by the principal investigator of this trial.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MAXI Collagen drink	MAXI Collagen drink	consume 1 bottle (50mL) per day
Placebo drink	Placebo drink	consume 1 bottle (50mL) per day
Normal fish collagen drink	Normal fish collagen drink	consume 1 bottle (50mL) per day

Primary Outcome Measures

Name	Time	Method
The change of skin collagen density	Day 0, Day 7, Day 28	DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units
The change of skin elasticity	Day 0, Day 7, Day 28	Cutometer® Dual MPA 580 was utilized to measure skin elasticity. Units: arbitrary units
The change of skin texture	Day 0, Day 7, Day 28	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin moisture	Day 0, Day 7, Day 28	Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

Secondary Outcome Measures

Name	Time	Method
The change of transepidermal water loss (TEWL)	Day 0, Day 7, Day 28	Tewameter® TM 300 was utilized to measure TEWL. Units: g/hm²
The change of skin wrinkles	Day 0, Day 7, Day 28	VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of self-assessment skin condition	Day 0, Day 7, Day 28	A self-assessment questionnaire was collected to evaluate skin condition
The change of skin pores	Day 0, Day 7, Day 28	VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units
The change of skin colour	Day 0, Day 7, Day 28	PANTONE® CAPSURE™ RM200-PT01 was utilized to measure skin colour. Units: arbitrary units

Trial Locations

Locations (1)

Department of Applied Cosmetology, Hungkuang University; 🇨🇳 Taichung City, Taiwan