Evaluation of Antioxidant and Skin Beauty Effects of Cherry Collagen Drink
- Conditions
- Skin Condition
- Interventions
- Dietary Supplement: Cherry collagen drinkDietary Supplement: Placebo drink
- Registration Number
- NCT05376657
- Lead Sponsor
- TCI Co., Ltd.
- Brief Summary
To assess cherry collagen drink on skin condition improvement
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Healthy adults aged above 20 years old
- Subject who is not willing to participate in this study.
- Patients with diseases of the skin, liver, kidney.
- Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- Constant drug use
- Students who are currently taking courses taught by the principal investigator of this trial.
- Body weight < 50 kg.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Cherry collagen drink Cherry collagen drink - Placebo drink Placebo drink -
- Primary Outcome Measures
Name Time Method The change of skin wrinkles Change from Baseline skin wrinkles at 8 weeks VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin texture Change from Baseline skin texture at 8 weeks VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density Change from Baseline skin collagen density at 8 weeks DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units
The change of skin elasticity Change from Baseline skin elasticity at 8 weeks Soft Plus was utilized to measure skin elasticity. Units: arbitrary units
- Secondary Outcome Measures
Name Time Method The change of skin melanin index Change from Baseline skin melanin index at 8 weeks Soft Plus was utilized to measure skin melanin index. Units: arbitrary units
The change of skin moisture Change from Baseline skin moisture at 8 weeks Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin spots Change from Baseline skin spots at 8 weeks VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units
The change of skin brown spots Change from Baseline skin brown spots at 8 weeks VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units
The change of SOD-RBC of blood Change from Baseline SOD-RBC at 8 weeks Venous blood was sampled to measure SOD-RBC
The change of desmosine of blood Change from Baseline desmosine at 8 weeks Venous blood was sampled to measure concentrations of desmosine
The change of TNF-alpha of blood Change from Baseline TNF-alpha at 8 weeks Venous blood was sampled to measure concentrations of TNF-alpha
The change of transepidermal water loss (TEWL) Change from Baseline TEWL at 8 weeks Tewameter® TM300 was utilized to measure TEWL. Units: g/hm²
The change of skin UV spots Change from Baseline skin UV spots at 8 weeks VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units
The change of t-GSH of blood Change from Baseline t-GSH at 8 weeks Venous blood was sampled to measure t-GSH
The change of GST-RBC of blood Change from Baseline GST-RBC at 8 weeks Venous blood was sampled to measure GST-RBC
The change of skin L* value Change from Baseline L* value at 8 weeks Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100
The change of blood total antioxidant capacity (TAC) Change from Baseline TAC at 8 weeks Venous blood was sampled to measure concentrations of TAC
Trial Locations
- Locations (1)
Chia Nan University of Pharmacy & Science
🇨🇳Tainan City, Taiwan