Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid

Not Applicable

Completed

• Conditions: Sleep Disturbance; Skin Condition

• Registration Number: NCT05182814
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess Collagen Drink on skin condition and sleep quality improvement

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-10
• Study First Submitted: 2022-01-04
• Study First Submitted QC: 2022-01-04
• Study First Posted: 2022-01-10
• Primary Completion: 2022-02-28
• Status Verified: 2022-03
• Study Completion: 2022-04-30
• Last Update Submitted: 2022-06-09
• Last Update Posted: 2022-06-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Healthy adults aged above 20 years old

Exclusion Criteria

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing
• Constant drug use
• Received facial laser therapy, chemical peeling or UV overexposure (>3 hours everyday) in the past 4 weeks.
• Students taught by the PI

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The change of skin elasticity	Change from Baseline skin elasticity at 8 weeks	Cutometer® MPA580 was utilized to measure skin elasticity. Units: arbitrary units
The change of skin L* value	Change from Baseline L* value at 8 weeks	Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100
The change of sleep quality	Change from Baseline sleep quality at 8 weeks	Self-assessment questionnaire was utilized to survey sleep quality.
The change of AGEs of blood	Change from Baseline AGEs at 8 weeks	Venous blood was sampled to measure AGEs
The change of TIMP-1 of blood	Change from Baseline TIMP-1 at 8 weeks	Venous blood was sampled to measure TIMP-1
The change of desmosine of blood	Change from Baseline desmosine at 8 weeks	Venous blood was sampled to measure desmosine
The change of skin wrinkles	Change from Baseline skin wrinkles at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin texture	Change from Baseline skin texture at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density	Change from Baseline skin collagen density at 8 weeks	DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units

Secondary Outcome Measures

Name	Time	Method
The change of skin melanin index	Change from Baseline skin melanin index at 8 weeks	Soft Plus was utilized to measure skin melanin index. Units: arbitrary units
The change of skin pores	Change from Baseline skin pores at 8 weeks	VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units
The change of skin a* value	Change from Baseline skin a* value at 8 weeks	Chroma Meter MM500 was utilized to measure skin a\* value. Units: arbitrary units
The change of skin hydration	Change from Baseline skin hydration at 8 weeks	Corneometer® CM825 was utilized to measure skin hydration. Units: arbitrary Corneometer® units 0-120
The change of transepidermal water loss	Change from Baseline transepidermal water loss at 8 weeks	Tewameter® TM300 was utilized to measure skin hydration. Units: g/hm²

Trial Locations

Locations (1)

Chia Nan University of Pharmacy ＆ Science; 🇨🇳 Tainan, Taiwan