Cognitive Training & a Healthy, Active Lifestyle Program for Patients with isolated REM-Sleep Behavior Disorder: CogTrAiL-RBD - CogTrAiL-RBD

niversität zu Köln0 个研究点目标入组 80 人开始时间: 2022年3月11日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients with iRBD:
•PSG-proven diagnosis of iRBD, which indicates a high probability for phenoconversion to Parkinson’s disease (ICD-10 G20) according to the criteria of the Movement Disorder Society (Berg et al., 2015; Heinzel et al., 2019) and the risk for developing mild cognitive impairment (ICD-10 F06.7)
•Age between 40-80 years
•Normal or corrected-to-normal vision and hearing
•German as native tongue or sufficient German language proficiency
•Sufficient computer knowledge and access to a local (laptop) computer with access to the internet
•Healthy control group:
•Age between 40-80 years
•Normal or corrected-to-normal vision and hearing
•German as native tongue or sufficient German language proficiency

•Patients with iRBD:
•Severe cognitive dysfunction (MoCA = 22)
•Limited resp. No capacity to consent
•Significant concomitant neurological and psychiatric resp. life-threatening diseases (e.g. acute episodes of mood disorders, personality disorders, psychoses or somatoform disorder)
•Additionally for those patients who consent to participate in MRI-measurement:
•Contraindications for MRI
•o Objects in or at one’s body that are MRI-incompatible and indelible (e.g. neurostimulator, pacemaker, grinding work on metal)
•o Big tattoos (above 20cm)
•o Actual or possible pregnancy
•o Fear of tight spaces
•Healthy control group:
•Severe cognitive dysfunction (MoCA = 22)
•Limited resp. No capacity to consent
•Significant concomitant neurological and psychiatric resp. life-threatening diseases (e.g. acute episodes of mood disorders, personality disorders, psychoses or somatoform disorder)
•Contraindications for MRI

发起方

niversität zu Köln