Structural and Functional Repercussions of Pulmonary Tuberculosis Sequelae
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Correlation between extent of pulmonary disease by computed tomography and lung volumes by spirometry
研究概览
简要总结
The study assesses patients with cured pulmonary tuberculosis by compulsory notification data of Uberlândia (Minas Gerais state - Brazil) from 2012, 2013, 2014 and 2015. These patients will be invited by telephonic contact. After eligibility and exclusion criteria evaluation, those included will be assessed in order to know structural and functional repercussions of pulmonary tuberculosis sequelae.
详细描述
This study evaluates structural and functional repercussions of pulmonary tuberculosis sequelae by chest imaging (computed tomography and radiograph), functional respiratory tests (spirometry and six minute walking test) in patients with cured pulmonary tuberculosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pulmonary tuberculosis with completed treatment (patients that received at least six months of treatment and with confirmed cure by negative culture and/or sputum smear, or clinical and radiological improvement after well succeed treatment);
- •Treatment finalized at least one year before.
排除标准
- •Physically impaired to perform the functional tests;
- •Coexisting lung pathology (history of previous respiratory disease or clinical or radiological evidence of lung disease other than tuberculosis);
- •Pregnants.
结局指标
主要结局
Correlation between extent of pulmonary disease by computed tomography and lung volumes by spirometry
时间窗: At least one year after completion of the tuberculosis treatment
High resolution computed tomography of the lungs will be evaluated by radiologists and the extent of pulmonary abnormalities will be score subjectively. Spirometry will permit assessment of lung volumes: forced expiratory volume in one second (FEV1) and forced vital capacity (FVC).
次要结局
未报告次要终点
研究者
Michelle Godoy Canazza Damian
Post-graduating in Clinical Sciences of Federal University of Uberlândia; Radiologist.
Federal University of Uberlandia