Breath-assisted stimulation of the anti-inflammatory reflex of the vagus nerve in covid-19 disease: a randomized-controlled trial - BEAT-COVID (Breathing against COVID)

Klinik für Psychosomatische Medizin und Psychotherapie, Uniklinik Ulm0 个研究点目标入组 48 人开始时间: 2021年2月2日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•SARS-CoV-2-infected patients hospitalized in normal wards (Not ICU) with a maximum moderate degree of disease according to RKI/WHO definition (see first exclusion criterion)
•- Age min. 18 years
•- Able to give informed consent at the time of study inclusion

•- severe covid pneumonia with fever and bilateral lung infiltrates and respiratory rate>30/min or SpO2<90% on room air (adapted from RKI/WHO)
•- Condition after surgery/trauma/acute event (stroke, myocardial infarction, acute covid-independent infection) in the last 4 weeks
•- Known pregnancy
•- Patients with pre-existing pulmonary disease who were on oxygen prior to infection (e.g., due to pulmonary fibrosis, COPD)
•- limited ability to give consent (e.g. due to dementia)
•- limited ability to perform breathing maneuvers independently (e.g. high frailty)
•- limited ability to provide self-care (care level 2 or 3)
•- lack of language skills
•- seizures in the medical history

发起方

Klinik für Psychosomatische Medizin und Psychotherapie, Uniklinik Ulm