Comparison of Flow-Controlled Ventilation and Volume-Controlled Ventilation on Respiratory Mechanics During Suspension Laryngoscopy: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 71
- 试验地点
- 1
研究概览
简要总结
Suspension laryngoscopy presents significant challenges for airway management due to the need to maintain adequate ventilation while providing optimal surgical exposure. Flow-controlled ventilation (FCV) is a novel ventilation mode that delivers constant inspiratory and expiratory flow using a narrow-lumen, cuffed endotracheal tube, potentially improving ventilation efficiency in shared-airway surgeries.
This prospective observational study aims to compare flow-controlled ventilation and conventional volume-controlled ventilation in patients undergoing elective suspension laryngoscopy. Respiratory mechanics, hemodynamic parameters, perioperative pulmonary function, and procedure-related complications will be evaluated to assess the feasibility and clinical performance of FCV in this surgical setting.
详细描述
Suspension laryngoscopy is a shared-airway surgical procedure that requires optimal visualization of the operative field while maintaining adequate ventilation and oxygenation. Conventional ventilation strategies may be associated with increased airway pressures and limited surgical exposure due to the use of standard endotracheal tubes. Flow-controlled ventilation (FCV) is a ventilation mode characterized by constant inspiratory and expiratory flow, which may offer advantages in procedures requiring a narrow airway device.
This prospective, non-randomized, observational comparative study evaluates adult patients undergoing elective suspension laryngoscopy. The choice of ventilation strategy-flow-controlled ventilation or conventional volume-controlled ventilation-was based on the attending anesthesiologist's clinical preference, reflecting routine clinical practice. All patients provided written informed consent prior to participation.
In both groups, standardized anesthetic management was applied, and ventilation parameters were adjusted to maintain normocapnia and adequate oxygenation. Intraoperative respiratory mechanics, including airway pressures and lung compliance, were recorded at predefined intervals. Hemodynamic parameters were monitored throughout the procedure. Pulmonary function tests were performed preoperatively and postoperatively using a portable spirometry device. Perioperative complications were documented.
The primary objective of this study is to compare intraoperative respiratory mechanics between flow-controlled and volume-controlled ventilation during suspension laryngoscopy. Secondary objectives include the assessment of perioperative hemodynamic parameters, changes in pulmonary function, and procedure-related complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients aged 18 to 65 years
- •American Society of Anesthesiologists (ASA) physical status I-III
- •Scheduled for elective suspension laryngoscopy under general anesthesia
- •Body mass index between 18 and 40 kg/m²
- •Provision of written informed consent
排除标准
- •Severe cardiac, pulmonary, hepatic, or renal disease
- •Inability to cooperate with pulmonary function testing
- •Intraoperative hemodynamic instability or oxygen desaturation (SpO₂ <92%)
- •Requirement for tracheostomy during the procedure
研究者
Salih Birkan Arı
M.D. Principal investigator
Ankara Training and Research Hospital
