Effect of 3D Kinect Games With Google Cardboard on Motor Control, Cognition, and Quality of Life in Mild to Moderate Alzheimer's Patient
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Cognition
研究概览
简要总结
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia that accounting for 60% to 80% of all cases (Better, et al., 2023). According to world health organization (WHO), more than 55 million people globally live with dementia, and this number is expected to rise to 78 million by 2023 and 139 million by 2050 (WHO, 2021).
详细描述
In the line with global epidemiology trend, the prevalence of AD is also rising at the regional level. In the United States, approximately 6.2 million individual aged 65 and older recently living with AD, and this figured is expected to reach 13.8 million by 2060 (Doher et al., 2023). Similarly, in Europe, the prevalence of AD is estimated at 5.05%, with a notably higher incidence in women (7.13%) as compared to men (3.31%) (Niu et al., 2017). Moreover, Asia alone has a higher prevalence of dementia patients than both America and Europe. A study conducted in tertiary care centers in Karachi showed that 63% of dementia patients had AD (Siddiqui et al., 2018).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
盲法说明
All participants will be blinded regarding treatment. A total of 38 patients will be recruited and assigned into two groups. Group A will receive Kinect Xbox game therapy exercises and Group B will receive Conventional Circuit Exercises
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Alzheimer's disease of age between 50-85 years.
- •Diagnosed AD stage Mild to Moderate.
排除标准
- •Undiagnosed AD patients.
- •Mental or neurological conditions like schizophrenia, Parkinson's, or stroke.
研究组 & 干预措施
Arms 1
Arm Description: Game-Based Rehabilitation received total 30sessions, 30 minutes/session, 5 times/week for total 6 weeks.
干预措施: 3D Kinect based game (Other)
Arm 2
Arm Description: Conventional Rehabilitation received total 30 sessions, 30 minutes/session, 5 times/week for total 6 weeks.
干预措施: Conventional therapy group (Other)
结局指标
主要结局
Cognition
时间窗: Baseline
Cognitive function will be assessed through among mild to moderate AD patients where low values indicate decrease in cognitive ability.
Cognition
时间窗: After 6 week of Intervention
Cognitive function will be assessed through Mini- Cog among Mild to Moderate AD patients where low values indicate decrease cognitive function
Motor Function
时间窗: Baseline
Motor function will be assessed using the Timed Up and Go (TUG) Test among patients with mild to moderate Alzheimer's disease (AD), where higher scores (longer completion times) indicate poorer functional mobility
Motor Function
时间窗: After 6 week of intervention
Motor function will be assessed using the Timed Up and Go (TUG) Test among patients with mild to moderate Alzheimer's disease (AD), where higher scores (longer completion times) indicate functional mobility
Quality of Life (QOL)
时间窗: Baseline
Quality of life will be assessed using the Quality of Life in Alzheimer's Disease (QOL-AD) scale among patients with mild to moderate Alzheimer's disease. Lower scores indicate poorer quality of life, whereas higher scores indicate better perceived quality of life.
Quality Of Life (QOL)
时间窗: After 6 weeks of Intervention
Quality of life will be assessed using the Quality of Life in Alzheimer's Disease (QOL-AD) scale among patients with mild to moderate Alzheimer's disease. Lower scores indicate poorer quality of life, whereas higher scores indicate better perceived quality of life.
次要结局
未报告次要终点