Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 480
- 试验地点
- 2
- 主要终点
- Intake of raw fish
研究概览
简要总结
Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer, alcohol intake, taking certain medicines (praziquantel), low intake of fresh vegetable, and low education. In 2015, researchers from Khon Kaen University developed the Community-based Health Education and Communication (CHEC) program to prevent liver cancer caused by liver flukes in communities of the Khon Kaen province, Thailand.
The main aim of this 5-year research study is to enhance the CHEC program to prevent liver cancer, and test if it is effective in improving the knowledge and behaviours of community residents regarding how to prevent liver cancer. This study will take place in Khon Kaen, Thailand. Other aims are to:
- Increase understanding in the community that make it difficult to prevent liver cancer, as well as community characteristics that can help prevent liver cancer;
- Incorporate the program we develop in healthcare to prevent liver cancer in Thailand.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •any individual residing in one of the 16 villages selected in the Khon Kaen province of Thailand, aged 20 and older
排除标准
- •any individual 19 years or younger
- •any individual not residing in one of the 16 pre-selected villages in the Khon Kaen province of Thailand
研究组 & 干预措施
Usual Care Community
Participants in this arm will not be given the eCHEC program
eCHEC Community
Participants in this arm will be given the eCHEC program as their intervention
干预措施: eCHEC program (Behavioral)
结局指标
主要结局
Intake of raw fish
时间窗: 12 months
Mean difference in the self-reported frequency of intake of raw fish in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Smoking
时间窗: 12 months
Difference in the proportion of smoking habits in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Stages of change for risk behaviours affecting the development of CCA.
时间窗: 12 months
Mean difference in the stages of change for risk behaviours in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Intake of fruits and vegetables
时间窗: 12 months
Mean difference in the self-reported frequency of intake of fruits and vegetables in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Stool test (proportion of stool test concentration)
时间窗: 12 months
Difference in the proportion of positive stool test of concentration of O. viverrini, pre- and post-intervention.
Alcoholic beverage intake
时间窗: 12 months
Mean difference in the intake of alcoholic beverages in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Praziquantel use
时间窗: 12 months
Difference in the proportion of use of the medication praziquantel (prescribed or self-medicated) in the intervention group compared to the control group. Self reported, pre- and post- intervention.
Stool test (mean concentration)
时间窗: 12 months
Difference in the mean concentration of O. viverrini in the stool test, pre- and post-intervention.
次要结局
- BMI(12 months)
- Quality of life(12 months)
- Waist circumference(12 months)
- Blood pressure(12 months)
- Health literacy(12 months)
- Knowledge of preventative measures against CCA(12 months)