NCT05653765进行中（未招募）不适用
Prognostic Value of the Angio-based Microvascular Resistance Use One Single Angiographic View Measured After Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction Patients
Henan Institute of Cardiovascular Epidemiology5 个研究点 分布在 1 个国家目标入组 2,663 人开始时间: 2022年12月20日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,663
- 试验地点
- 5
- 主要终点
- MACEs
研究概览
简要总结
The goal of this observational study is to learn about in STEMI with Primary PCI Patients. The main questions it aims to answer are:
- To determine the value of AMR in predicting the long-term clinical prognosis of patients with STEMI after PPCI, and to find the best cut-off value.
- Analyze the factors of PPCI affecting AMR and explore the effective measures of PPCI microcirculation protection.
Radiographic images of STEMI receiving primary PCI treatment in several chest pain centers in China will be included. The last image of the infarct-related vessel will be used as a target to calculate its AMR. The relationship between AMR and long-term clinical prognosis was analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 or older
- •Type 1 myocardial infarction
- •Receive PPCI
排除标准
- •Failed to identify culprit vessels.
- •Structural heart disease with moderate to severe aortic valve or mitral regurgitation and or stenosis that may affect cardiac function
- •Dialysis patients with severe renal insufficiency
- •Severe and uncontrollable arrhythmia
- •Complicated with dilated cardiomyopathy
- •Unable to tolerate dual antiplatelet therapy
- •Severe and uncontrollable anemia
- •Hyperthyroidism
- •TIMI blood flow 0-1 grade after PPCI
结局指标
主要结局
MACEs
时间窗: 12 months
cardiac death, hospitalization for heart failure, target vessel revascularization，non-fatal MI
次要结局
- cardiac death(12 months)
- hospitalization for heart failure(12 months)
- target lesion revascularization(12 months)
- Repeated myocardial infarction(12 months)
研究者
研究点 (5)
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