Comparison of the Satiating Effects of Differentially Processed Isolated Soy Proteins
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Subjective Satiety
研究概览
简要总结
Proteins are known to be more satiating than the other macronutrients; however, the type and amount of protein needed to induce a significant effect on satiety (fullness between meals) is sometimes difficult to determine. In this study, 2 differentially processed isolated soy proteins will be tested for satiety using subjective visual analogue scales. The amount of food consumed following intake of the isolated soy proteins will be measured 3 hours after consuming the proteins. The hypothesis is that differentially processed isolated soy proteins will show unique satiety responses.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 20 and 30 kg/m2
- •Age between 18-65y
- •Unrestrained eater (score<12)
- •Regularly consume 3 meals per day
- •Moderate exercise (eg running, aerobics classes, other sports activities) of no more than 7 hours per week
排除标准
- •use of drugs that influence carbohydrate or lipid metabolism (eg. hypoglycemic agents, antibiotics taken less than 6 weeks before study entry, glucocorticoids, anti-diarrheal medication, weight loss medication, and anti-diabetic medication)
- •presence of any significant disease (eg gastrointestinal diseases, diabetes, a CVD event less than 12 weeks from study entry, current hepatic disease, etc)
- •use of special dietary treatments within 4 weeks of study (eg weight loss diet, extremely high or low carbohydrate/protein/fat diet, use of meal replacements more than once a day)
- •use of supplements within 1 week of study (does not include vitamin supplements or supplements which are routinely taken and were initiated 4 weeks before the study and which will be continued during the study period)
- •restrained eater (score>12)
- •weight change (absolute body weight change of ≥ 10%) within the previous 6 weeks
- •alcohol intake >2 drinks/day
- •food allergies of any kind
- •swallowing difficulties
- •exercising more than 7 hours per week
研究组 & 干预措施
Test ISP-10
10 grams of the test ISP will be consumed as a dry-blended beverage
干预措施: Dry-Blended Beverage (Dietary Supplement)
Test ISP-20
20 grams of the test ISP will be consumed as a dry-blended beverage
干预措施: Dry-Blended Beverage (Dietary Supplement)
Control ISP-10
10 grams of the control ISP will be consumed as a dry-blended beverage
干预措施: Dry-Blended Beverage (Dietary Supplement)
Control ISP-20
20 grams of the control ISP will be consumed as a dry-blended beverage
干预措施: Dry-Blended Beverage (Dietary Supplement)
结局指标
主要结局
Subjective Satiety
时间窗: 3 hours
Measure subjective satiety using visual analogue scales
次要结局
- Ad Libitum Food Intake(30 minutes)