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临床试验/NL-OMON52823
NL-OMON52823尚未招募不适用

Effect of sodium oxybate on energy metabolism in narcolepsy - Sodium oxybate and energy metabolism in narcolepsy

eids Universitair Medisch Centrum0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • •1. Narcolepsy type 1 based on ICSD-3 criteria.
  • •2. >=18 and <40 years of age.
  • •3. Biologically female.
  • •4. White Caucasian descent.
  • •5. Clinical indication for SXB treatment.
  • •6. BMI >= 25 kg/m2
  • •Matched controls:
  • •1. Biologically female.
  • •2. Age- and BMI-match with patient.
  • •3. White Caucasian descent.

排除标准

  • •Patients and matched controls:
  • •1. Previous use of SXB.
  • •2. Contraindications for SXB treatment.
  • •3. Sleep-wake disorders other than narcolepsy type 1.
  • •4. Renal, hepatic or endocrine disease.
  • •5. Use of medication known to influence glucose and/or lipid metabolism or
  • •brown adipose tissue activity (e.g. β-adrenergic receptor blockers).
  • •6. Participation in an intensive weight-loss program or vigorous exercise
  • •program during the year before the start of the study.
  • •7. Pregnant during the study days (due to unreliable body composition
  • •measurements on the InBody machine)

研究者

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