CTRI/2025/12/099712尚未招募4 期
A Randomised Study to compare intravenous Labetalol versus Lignocaine for Attenuation of Hemodynamic response to Laryngoscopy and Endotracheal intubation in ,SMS Medical college,Jaipur.
SMS Medical college Jaipur1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2026年1月5日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- To determine the difference in changes in heart rate from baseline to different time intervals in two groups.
研究概览
简要总结
In this study we will compare effectiveness of intravenous labetalol(0.75mg/kg) and lignocaine (1.5mg/kg) for attenuating the hemodynamic responses to laryngoscopy and endotracheal intubation in adult patients undergoing surgeries under general anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient undergoing elective surgical procedures under general anaesthesia and endotracheal intubation.
- •2.Patients willing to give written and Informed consent.
- •Adult patients aged 18 to 60 years.
- •5.Patients belonging to ASA (American society of Anesthesiologist ) grade I.
排除标准
- •History of chest pain/syncope/palpitations.
- •Any contraindications or history of hypersensitivity to study drugs.
- •Any respiratory problems.
- •Hepatic and renal issues.
- •Any abnormalities in the ECG.
- •Anticipated difficult intubation.
- •Patient should not be a part of any other study.
结局指标
主要结局
To determine the difference in changes in heart rate from baseline to different time intervals in two groups.
时间窗: 0,1,3,5,10 minutes after intubation.
次要结局
- To determine the difference in changes in hemodynamic responses (SBP,DBP,MAP)from baseline to different time intervals in two groups.(0,1,3,5,10 minutes after intubation.)
研究者
Dr Sunil Chauhan
SMS Medical college and Hospital Jaipur
研究点 (1)
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