NCT01494389Unknown不适用
The Role of CD4+T Lymphocyte Subsets in Cell Immunity in Patients With Sepsis
Chinese PLA General Hospital1 个研究点 分布在 1 个国家开始时间: 2011年8月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to explore the value of CD4+T lymphocyte subsets in cell immunity in the patients with sepsis.There are immunoparalysis in septic patients,the important player is the change of CD4+T lymphocyte,this immunoparalysis state contribute to the illness progress and outcome. Comprehend the change regularity of septic patients' cell immunity can guide fiter and correcter treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male and female aged 18 years old and over;
- •Fulfilled at least two criteria of systemic inflammatory response syndrome (a) core temperature higher than 38 °C or lower than 36 °C (b)respiratory rate above 20/min, or PCO2 below 32 mmHg (c) pulse rate above 90/min, and (d) white blood cell count greater than 12,000/μl or lower than < 4,000/μl or less than 10% of bands.
- •Clinically suspected infection;
排除标准
- •were under 18 years of age;
- •were refused by the patients or his/her familiality;
- •were suffering from acquired immunodeficiency syndrome,virlhepatitis,autoimmune diseases and hematology;
- •use medicine which can affect immune system,such as Glucocorticoid and Immunosuppressant
- •died within 24h after being taken into the ICU, or refused to get involved in the study, or gave up treatment during the period of observation
研究者
研究点 (1)
Loading locations...
相似试验
尚未招募
Unknown
Evaluation of CD4 T cell count and its subsets in patients with major depressive disorderCTRI/2024/07/071516Maulana Azad Medical College
招募中
不适用
Pathogenicity of B and CD4 T Cell Subsets in Multiple SclerosisMultiple SclerosisClinically Isolated SyndromeNCT04798651University Hospital, Bordeaux150
已完成
4 期
Comparison of Three Licensed Influenza VaccinesInfluenzaNCT03068949University of Rochester413
终止
4 期
Adaptive Immune Responses and Repertoire in Influenza Vaccination and Infection (SLVP031)InfluenzaNCT03028987Stanford University10
招募中
不适用
CD4+ T cells and immune ageing; major players and predictors for disease activity in giant cell arteritisLarge vessel vasculitis and Polymyalgia rheumatica1000381610010761NL-OMON44732niversitair Medisch Centrum Groningen1,500