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临床试验/NCT03321786
NCT03321786已完成不适用

Legionella Pneumonia's Effect on Olfactory Function

University of Pennsylvania1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2017年9月6日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Score on the University of Pennsylvania Smell Identification Test

研究概览

简要总结

The goal of this study is to determine whether survivors of Legionnaires' disease suffer smell loss. A quantitative olfactory test will be performed by the participants. Such testing will require approximately 20-30 minutes of the participant's time. The participants will take the University of Pennsylvania Smell Identification Test (UPSIT), a scratch-and-sniff test to assess their ability to identify odors in a forced- choice format. Volunteers will also complete a questionnaire asking personal history, demographic questions, and medical history.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Persons of generally good health, as obtained from a screening questionnaire who are 18 years of age and older
  • Both men and women of all ethnic backgrounds will be accepted.

排除标准

  • Age less than 18
  • Pregnant Women
  • Persons who mental competence is limited, such as those with dementia

结局指标

主要结局

Score on the University of Pennsylvania Smell Identification Test

时间窗: 20-30 Minutes

The number of correct odor identification responses out of 40 from the standardized University of Pennsylvania Smell Identification Test. The total number of correct responses will then be compared to standard norms of correct responses based on demographic information such as age and sex. Comparing the scores to the standard norms collected will indicate whether a volunteer is normosmic, hyposmic, or anosmic.

次要结局

  • Questionnaire Responses(20-30 Minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Doty

Director, Smell and Taste Center, Professor of Psychology in Otorhinolaryngology: Head and Neck Surgery

University of Pennsylvania

研究点 (1)

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