Effect of Scalp Nerve Block with levobupivacaine and ketamine versus levobupivacaine only on intraoperative opioid requirements and postoperative analgesia in Patients Undergoing supratentorial craniotomy: A Randomized control trial. - nil

All India Institute of Medical Sciences, Bathinda0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年3月4日

研究概览

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•1.Patients between 18-70 years of age
•2.Patients scheduled for elective supratentorial craniotomy, belonging to American Society of Anaesthesiologists (ASA) physical status I, II, or III.
•3.Patients undergoing intraoperative pin fixation of the head.
•4.Preoperative GCS 15
•5.Patients with an anticipated full awakening from general anaesthesia within 2 hours postoperatively.

•1.History of craniotomy with absent bone flap
•2.Frontal craniotomy
•3. Known psychiatric disorder
•4. Uncontrolled epilepsy
•5.Chronic headache.
•6. Peri-incisional infection
•7. No plan to extubate or expected prolonged mechanical ventilation.
•8.Known allergy to NSAIDS, ketamine, or levobupivacaine.
•9. Chronic opioid use ( >2 weeks) or history of excessive alcohol or drug abuse
•10. Inability to understand the use of NRS.
•11. Extremes of body mass index (BMI) ( <15 or >35 kg/cm2).
•12. Pregnant or breastfeeding.
•Withdrawal criteria
•1.Not awake 2 hours after surgery.
•2.Early revision within the first 48 hours.
•3.Voluntary withdrawal.
•4.Received radiation therapy and chemotherapy postoperatively.

发起方

All India Institute of Medical Sciences, Bathinda