Chinese Herbal Medicines for Menopausal Symptoms in Breast Cancer Patients: A Randomized, Double-blind, Controlled Study

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•? Patients with primary breast cancer (stage 0-III) by pathologic diagnosis and with menopausal symptoms;
•? Aged 25-60 years;
•? Patients are undergoing endocrine therapy for more than 3 months;
•? The subjects experienced at least 4 times of moderate and severe hot flashes every day;
•? The Karnofsky score is greater than or equal to 60 points;
•? The predicted survival time is greater than or equal to 6 months;
•? Voluntarily sign the informed consent file.

•? Patients with recurrent, metastatic breast cancer or other cancer diagnosed by imaging or histology;
•? Patients who cannot adhere to endocrine therapy;
•? Uncontrolled and/or diagnosed medical conditions such as severe liver, kidney, heart, and brain diseases; abnormal bone marrow function; Uncontrolled or untreated hypertension (SBP >160mmHg and/or DBP > 100mmHg), Uncontrolled or untreated diabetes; Or abnormal thyrotropin may lead to symptoms similar to menopausal symptoms.
•? Pregnant and lactating women;
•? Participated in phase I and II clinical trials in the past 6 months or participated in phase III and IV clinical trials in 3 months;
•? Use other medications (e.g. tibolone, black cohosh extract or soy isoflavones, vitamins, etc.) for menopausal symptoms within 3 months;
•? Allergic to the tested drug.

发起方

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine