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临床试验/ISRCTN22078616
ISRCTN22078616已完成不适用

eutralization of a spondylotic cervical myelopathy dynamic compression effect: Impact of twodifferent surgical strategies.

niversity Hospital Centre Zagreb0 个研究点目标入组 60 人开始时间: 2016年1月21日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • 1. Clinical inclusion criteria:
  • CSM classified as Nurick 3-5 in whom left sided C3-C7 open door ECL or ACCF were done for decompression
  • 2. Radiological inclusion criteria were preoperative tethering detected by kMRI 3-D reconstructions. In addition, the patients’ postdecompression spinal cords were untethered, spinal cord shifted backward and the spinal cords dissociated motion from vertebral canal. Spinal cord and brainstem transverse sections obtained from kMRI were used to render 3-D reconstructions of lower part of the brainstem and cervical and upper thoracic spinal cord. Pons to T5/T6 models were used according to the following criteria:
  • 3. Spinal cord tethering: At the point of maximum compression canal compromise is graded 3 (pincer effect); through extension to flexion neck movement the two separate segments of the spinal cord changes the length. Pincer effect divides this two segment.
  • 4. Spinal cord untethering and dissociation of motion: The spinal cord and subarchnoidal space are without compression and therefore graded as 0. The spinal cord homogeneously increases its length from extension to flexion. Preoperative spinal cord 3-D model represents original spinal canal and is compared with postoperative. Dissociation of motion is considered when postoperative 3-D model does not cover pre-opartative, but is shorter and less curly.
  • 5. Backward shift: Preoperative subaxial spinal cord central spline was superposed on the central spline created on the postoperative images. Backward shift is considered when instead of superposing of two lines the postoperative central spline is placed porsterior to the preoperative

排除标准

  • Patients with:
  • 1. Kyphosis more than 10 degrees
  • 2. Instability
  • 3. Metabolic or inflammatory bone disease
  • 5. Multiple sclerosis
  • 6. Anterolateral sclerosis
  • 7. Toxic-metabolic myelopathies

研究者

发起方
niversity Hospital Centre Zagreb

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