Assessment of Neuropathic Pain
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Pain, sensory and autonomic assessments
研究概览
简要总结
Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases. The functionality of the pain pathway in humans as well as its plastic changes following SCI can be assessed in vivo by surface electrophysiological recordings and functional magnetic resonance imaging after noxious heat stimulation of the skin. Aims: a) establishing a clinically applicable assessment of the pain pathway and characterizing its changes as a consequence of SCI and in peripheral nerve diseases in an objective manner, b) characterizing plastic changes in the pain pathway in SCI patients with neuropathic pain and in patients with peripheral nerve diseases and relating them to the development of neuropathic pain syndromes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Uninjured
- •Scord injured subjects
- •Subjects with peripheral nerve diseases
- •Patients resident in Switzerland
排除标准
- •Presence of any central psychiatric disorder (that precludes subject from giving informed and voluntary consent)
- •For fMRI measurements: "yes" for any item in the MR-risk questionnaire
- •Patients resident outside from Switzerland
结局指标
主要结局
Pain, sensory and autonomic assessments
时间窗: 2 - 4 weeks
次要结局
未报告次要终点